Several antibiotics have been discovered following the discovery of penicillin in 1928 by Scottish Scientist and Nobel Laureate Alexander Fleming. Antibiotics have come a long way to cure infectious diseases. Today more than 100 different kinds of antibiotics have been discovered. The antibiotics have been found to cure various kind of infectious disease caused by microbes, but the advent of drug resistance in them also known as SUPERBUGS has pose new challenges for researchers. The advent of multiple drug resistance in microbes has posed new challenge to researchers. The scientists are now evaluating alternatives for combating infectious diseases. Focus on major alternatives to antibiotics; these promising anti-microbial include phages, bacteriocins, killing factors, antibacterial activities of non-antibiotic drugs and quorum quenching. This session focuses more on treatment and therapeutics of infectious diseases.