Infections caused in hospitals, nursing homes, healthcare units are called nosocomial infections. Nosocomial infections are also known as hospital hospital-acquired infections (HAIs). Bacteria, fungus, and viruses cause HAIs, bacteria alone cause 90 percent of Nosocomial infections. Nosocomial infections are caused when immune systems are compromised during a stay in a hospital or a clinic facility. Generally, nosocomial infections are contacted from person to person, through unhygienic habits in people, and unclean surroundings, unsterilized medical instruments like respiratory machines, catheters, and other instruments. Nosocomial infections are also caused by unnecessary usage of antibiotics, which lead to bacteria becoming immune to or unaffected to irregular use of antibiotics. To avoid nosocomial infections sanitation procedures should be implemented in hospitals and clinical centers. Disinfecting the surface floors, sterilizing equipment and instruments, maintaining hygienic conditions in healthcare facilities, hospital settings, neat staff uniforms and other preventive measures need to be put in place. This session on nosocomial infections focuses on sanitation methods and examines other remedial measures to be adopted in hospital settings, clinical facilities, and various other means of keeping nosocomial infections away from the people.